- Overview
- Why Do Safety Pharmacology Studies?
- Our Services
- FAQs
Overview
Safety pharmacology is a branch of pharmacology that focuses on the assessment of the potential risks of new drugs on the cardiovascular, central nervous, and respiratory systems. By conducting safety pharmacology studies, researchers can identify any potential adverse effects of a drug before it is tested in humans.
In the field of biopharmaceuticals, the importance of safety pharmacology cannot be overstated. Understanding the potential risks and side effects of new drugs is crucial in the drug development process. Our company is committed to providing a range of services to support safety pharmacology research.
Why Do Safety Pharmacology Studies?
Safety pharmacology studies can help to predict potential side effects of a drug before they occur in clinical trials. By understanding how a drug interacts with various organ systems in the body, researchers can identify any potential risks and make informed decisions about whether a drug is safe for further testing in humans.
Our Services
We offer a comprehensive range of safety pharmacology services to support the drug development process. Our services are mainly as follows:
Cardiovascular Safety Assessments
Cardiovascular safety assessments are designed to evaluate the potential adverse effects of drugs and other compounds on physiological systems, particularly the cardiovascular system. These assessments are typically performed in preclinical animal models.
Our cardiovascular safety studies include digital physiological signal telemetrye. The main contents of our assessment are:
- Electrocardiogram
- Blood pressure
- Heart rate
- (QTcV) interval
- Internal temperature
Central Nervous System (CNS) Safety Assessments
CNS safety assessments are a crucial aspect of safety pharmacology studies aimed at evaluating the potential adverse effects of drugs and other compounds on the central nervous system. These assessments are essential for identifying and mitigating potential CNS-related risks associated with drug therapy.
Our CNS safety studies include spontaneous activity tests in mice. The main contents of our assessment are:
- Locomotor activity
- Learning and memory
- Behavior
- Coordination
- Sensory motor reflex
Respiratory Safety Assessments
Respiratory safety assessments in safety pharmacology studies refer to the evaluation of potential adverse effects on the respiratory system caused by pharmaceutical compounds. These assessments help determine the safety of drug candidates and identify whether they pose a risk to respiratory health.
Our respiratory safety studies include whole body plethysmography. The main contents of our assessment are:
- Tidal volume
- Minute volume
- Respiratory rate
- Lung resistance
- Lung compliance
Frequently Asked Questions (FAQs) About Safety Pharmacology
What are the research objectives of safety pharmacology?
The research objectives of safety pharmacology include evaluating the potential adverse effects of pharmaceuticals on vital organs and systems, assessing the potential for drug-induced toxicity, and determining the safety and tolerability of new drugs. This helps identify potential safety issues early in the drug development process to protect human health and improve drug safety.
How are safety pharmacology studies conducted?
Safety pharmacology studies are typically conducted using preclinical animal models, such as rodents or non-human primates. These studies involve administering test compounds to animals and monitoring their physiological responses using a variety of techniques, such as telemetry, electrocardiography, and respiratory measurements.