- Overview
- Advantages
- Our Services
Overview
Biocatalysis has become a rapidly growing area of process technology, especially in the pharmaceutical industry. It can be said that the introduction of biocatalysis offers new opportunities to develop green synthetic routes for pharmaceuticals.
Advantages of Biocatalysis in Pharmaceutical Synthesis
Biocatalysis has the inherent advantages of high selectivity and specificity, environmental sustainability and scalability, and provides a more environmentally friendly and economical method for the synthesis of drugs.
High Selectivity and Specificity
One of the key advantages of biocatalysis in pharmaceutical synthesis is its high selectivity and specificity. Enzymes exhibit excellent substrate specificity, often catalyzing reactions with regio-, stereo-, and enantioselectivity. This enables technologists to control the stereochemistry of drug molecules and minimize the formation of unwanted side products, leading to higher product purity and yield.
Environmental Sustainability
Biocatalysis embodies the principles of green and sustainable chemistry in pharmaceutical synthesis. Enzymatic reactions operate under mild conditions, often using water as the solvent and generating minimal waste. By replacing traditional chemical processes with biocatalytic alternatives, pharmaceutical companies can reduce their environmental footprint, comply with regulatory requirements, and achieve cost savings in production.
Scalability and Process Robustness
Enzymatic reactions can be easily scaled up from the laboratory to industrial production. This makes biocatalysis a versatile and practical option for large-scale pharmaceutical synthesis. In addition, enzymes have inherent stability under a variety of conditions, which makes them suitable for use in continuous flow systems and other process intensification strategies.
Our Services
With years of experience in the biopharmaceutical industry, our company provides comprehensive biocatalytic services and solutions to meet customer needs. Our services mainly include:
- Enzyme library screening
- Enzyme development
- Enzyme manufacturing
- Enzyme evolution
- Enzyme immobilization
- Process development and optimization
- Technology transfer
Our biocatalysis platform has completed a number of projects involving enzyme process development and process optimization. If you are interested in our biocatalysis platform, please feel free to contact us.