- Overview
- Applications
- Our Services
- Why Choose Us
Overview
Peptides are a class of compounds formed by connecting multiple amino acids through peptide bonds. Peptides hold immense potential in therapeutic applications due to their specificity, efficacy, and relatively low toxicity. However, their inherent limitations, such as poor stability and rapid degradation, often hinder their clinical utility. To overcome these challenges, researchers have been exploring peptide modification strategies to enhance their properties and widen their therapeutic scope.
As an important means to change the main chain structure or side chain group of peptide chain, peptide modification can effectively change the physical and chemical properties of peptide compounds, increase water solubility, prolong the action time in vivo, change their biological distribution, eliminate immunogenicity, and reduce toxic and side effects. Our company is committed to providing customers with peptide modification services. We have professional peptide synthesis capabilities and offer hundreds of peptide modification types to meet your diverse research needs. If you do not find the desired peptide modification in our list of services, please contact us immediately.
Applications
Modified peptides have great potential to treat a variety of diseases, including cancer, metabolic disorders and infectious diseases. Enhanced stability and pharmacokinetic profiles improve the efficacy and dosing regimen of peptide-based drugs.
Modified peptides can be utilized as vaccine candidates against infectious agents or cancer antigens. Optimization of peptide immunogenicity and antigen presentation enhances vaccine efficacy and induces robust immune responses.
Modified peptides conjugated to imaging agents enable targeted visualization of specific molecular targets in vivo. Peptide-based imaging probes can provide valuable insights into disease pathology and aid in diagnosis and therapeutic monitoring.
Our Services
N-terminal Modifications
- Acetylation
- Biotinylation
- Benzoyl
- Fatty Acid
- Phosphorylation, sulfation and glycosylation
- H (free amine)
- Fmoc
- CBZ
- Pyr
- Lipid tail
C-terminal Modifications
- Amidation
- Peptide alcohols and aldehydes modification
- C-terminal esters and thioesters
- Multiple Antigen Peptides (MAP)
- Bzl
- p-Nitroanilide
- Cysteamide
- -OH (free)
- -NH2
- -NH-Me
Isotope Labeling
- 1H-D
- 12C-13C
- 14N-15N
- 13C, 15N-Arg
- 13C, 15N-Ala
- 13C, 15N-Leu
- 13C, 15N-Lys
- 13C, 15N-Pro
- 13C, 15N-Phe
- 13C, 15N-Val
PTMs (Site Specific Modifications)
- Acetylation (Lys)
- Phosphorylation (Ser, Thr, Tyr)
- Methylation (Arg)
- Glycosylation
- Lipidation
- SUMOylation
- Ubiquitionation
Fluorescent Peptide Modifications/FRET Pairs
- 1-Pyrenemethylamine HCL
- 5-FAM (N-Terminal)
- 5-FAM-Ahx (N-Terminal)
- Abz (N-Terminal)
- DABCYL
- DABCYL/Glu(EDANS)-NH2
- Dansyl (N-Terminal)
- Dansyl-Ahx (N-Terminal)
- EDANS/DABCYL
- FITC (N-Terminal)
- FITC-Ahx (N-Terminal)
- Glu(EDANS)-NH2
- MCA (N-Terminal)
- MCA/DNP
- TMR
- AMC
Peptide Conjugates
- KLH (-NH2 of N terminal)
- KLH Conjugation on cysteine
- BSA (-COOH of C terminal)
- BSA Conjugation on cysteine
- OVA (-NH2 of N terminal)
- OVA (-COOH of C terminal) <
- OVA Conjugation on cysteine
Linker
- Gly
- Ava
- AEA
- GABA
- Beta-Ala
- Ahx
- Ado
- Mini-PEG
- Mini-PEG2
- Mini-PEG3
- PEG4
Why Choose Us
Expertise and Experience
Our company has a team of experts with extensive experience in the field of peptide modification. Whether N-terminal modification, C-terminal modification or other types of modification, we can provide a wide range of customized options to optimize peptide properties.
State-of-the-Art Technologies
Leveraging cutting-edge technologies and advanced equipment, our company remains at the forefront of innovation in peptide synthesis and modification.
Customized Solutions
Our company understands that every project is unique. Therefore, we offer customized solutions to meet the specific requirements of our clients.