- Overview
- Our Capabilities
- Why Choose Us
Overview
Drug metabolism and pharmacokinetics (DMPK) studies the absorption, distribution, metabolism and excretion (ADME) process of drugs in the body, as well as the pharmacological and toxicological effects of drugs. DMPK plays a crucial role in drug development because it helps researchers understand how drugs are processed in the body, how they interact with different biological systems, and how they are eliminated from the body. This information can be used to optimize drug dosing regimens, predict potential drug-drug interactions, and assess the safety and efficacy of new drugs.
We have established a DMPK drug discovery team with rich experience. We can not only provide you with accurate experimental data, but also provide you with data analysis and interpretation services. Please believe that your project goal is also the direction of our efforts. If you have any related needs, please feel free to contact us.
Our Capabilities
Our company provides comprehensive DMPK services. Our capabilities are mainly as follows:
In Vitro ADME
- In vitro absorption studies
- In vitro distribution studies
- In vitro metabolism studies
- In vitro excretion studies
In Vivo PK
- Rank-ordering compounds/formulations
- Bioavailability and bioequivalence
- Dose proportionality (ascending dose)
- Dose linearity (multiple dose)
- In vivo drug interactions
- Tissue distribution (non-radioactive and radioactive)
- Toxicokinetics
- Non-compartmental and compartmental pharmacokinetics
- Pharmacodynamic and pharmacokinetic/pharmacodynamics modeling
- Preclinical vehicle screening
Metabolite Identification
- In vitro metabolite identification
- In vivo metabolite identification
Why Choose Us
Regulatory Compliance and Quality Assurance
We adhere to the highest standards of quality and regulatory compliance to ensure the reliability and integrity of our DMPK studies. Our laboratories are equipped with state-of-the-art instrumentation and maintained in accordance with Good Laboratory Practice (GLP) guidelines. Additionally, our team of experts stays abreast of regulatory requirements and industry standards, providing clients with comprehensive documentation and regulatory support throughout the drug development process.
Timely and Cost-Effective Solutions
In today's fast-paced environment, time and cost efficiency are critical. Our company is committed to delivering cost-effective DMPK solutions in a timely manner without compromising quality. Our streamlined workflows and efficient project management ensure fast turnaround times, enabling clients to accelerate drug development and minimize costs. Additionally, our competitive pricing structure makes our services accessible to organizations of all sizes, from startups to multinational corporations.